Rapact 5mg tablet - Everolimus | Apple Pharmaceuticals

Description

Rapact 5mg consist of an active ingredient known as Everolimus which is intruded with the growth of cancer cell and the process is slowed down. Rapact 5mg tablets is not a curable medication, which helps to slow their spreading into the body.

Indication

Primarily Rapact 5mg tablets indicated for the treatment
* kidney carcinoma
* Breast carcinoma
* Brain carcinoma
Everolimus is also indicated in various advanced stage cancer in stomach, intestines or pancreas.

Mechanism Of Action

Everolimus is an inhibitor of mTOR, joins at high compatibility to FK506 binding protein 12, via producing drug complex that inhibits the productive of mTOR.
This inhibition reduces the activity of effectors downstream, which may lead to stoppage of cell progression from G1 into S phase, finally causes cell growth arrest and apoptosis

Dosage

Rapact 5mg tablets should be given with or without food.

Dosage regimen of Rapact 5mg:

In breast cancer, renal cell cancer, pancreatic cancer, Neuro endocrine cancer:
The prescribed dosage is 10mg should be taken as a single dose.

In Brain or intracranial cancer:

The prescribed dosage of Rapact as a single dose. is 4.5mg/m2 given orally

In pediatric:

The pediatric dosage of Rapact as a single dose in brain or intracranial tumor is 4.5mg/m2 should be given orally.

Drug Interaction

Rapact 5mg interaction with strong inhibitor of CYP3A4, or P-g p, cause reducing the efflux of Everolimus and high plasma concentration of Everolimus.
Interaction of Rapact 5mg with strong CYP3A4 inducers will increase the disclosure of Everolimus.
Combination of Rapact 5mg with cyclosporine will be increasing the AUC level of Everolimus frequently.

Contraindication

If patients are contraindicated to the components present in the Rapact 5mg tablets. Some anaphylactic reaction occurs.

Pregnancy

Pregnancy category of Everolimus C
In patients, Rapact 5mg is used only after knowing the benefits to the mother exceed the risk to the fetus.

Lactation

Breast feeding should not be suggested

Storage

Rapact 5mg tablet store at 25°C.
Store the medicine away from moisture, heat, and light

Missed Dose

In the case of the missed dose, patients must consult with a medical practitioner and follow the instructions given by them.
Thereby missed dose should be avoided and follow the regular dosing schedule.

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